SKU: WP1316 Categories: ,

MOG Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP1316-100
Enter the quantity you would like, or drag the panel to find the quantity and price that best for you
Bulk QuoteAuthorize OEM & ODM

Product details

Background:

The product of this gene is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetMOG
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)27kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 30-110
SpecificityMOG Polyclonal Antibody detects endogenous levels of protein.
Gene NameMOG
Protein NameMyelin-oligodendrocyte glycoprotein
Other Name
SpeciesHuman
Gene ID4340
UniprotQ16653,
Species.1Mouse
Gene ID.1
Uniprot.1Q61885,
Species.2Rat
Gene ID.2
Uniprot.2Q63345
Cellular Localization[Isoform 1]: Cell membrane; Multi-pass membrane protein .; [Isoform 5]: Cell membrane; Multi-pass membrane protein .; [Isoform 2]: Cell membrane; Single-pass type I membrane protein .; [Isoform 3]: Cell membrane; Single-pass type I membrane protein .; [Isoform 4]: Cell membrane; Single-pass type I membrane protein .; [Isoform 6]: Cell membrane; Single-pass type I membrane protein .; [Isoform 7]: Cell membrane; Single-pass type I membrane protein .; [Isoform 8]: Cell membrane; Single-pass type I membrane protein .; [Isoform 9]: Cell membrane; Single-pass type I membrane protein .
Tissue ExpressionFound exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes.
Signaling_pathway
Research Areas
FunctionAlternative products:Additional isoforms seem to exist,Caution:Do not confuse myelin-oligodendrocyte glycoprotein (MOG) with oligodendrocyte-myelin glycoprotein (OMG).,Function:Minor component of the myelin sheath. May be involved in completion and/or maintenance of the myelin sheath and in cell-cell communication.,online information:Myelin oligodendrocyte glycoprotein entry,similarity:Belongs to the immunoglobulin superfamily. BTN/MOG family.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:May form homo- or heterodimers between the different isoforms.,tissue specificity:Found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes.,
Please login to post questions
Back to Top
Product has been added to your cart