Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human MON1A
Specificity
This antibody detects endogenous levels of MON1A at Human, Mouse
Gene Name
MON1A SAND1
Protein Name
Vacuolar fusion protein MON1 homolog A
Other Name
Species
Human
Gene ID
84315
Uniprot
Q86VX9,
Species.1
Mouse
Gene ID.1
72825
Uniprot.1
Q6PDG8
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Tissue Expression
Signaling_pathway
Cellular Processes >> Transport and catabolism >> Mitophagy - animal
Research Areas
Function
Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes (By similarity). Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form .