Price range: $268.00 through $328.00
Background:
This gene encodes a member of a subfamily of non-clustered, diverged, antennapedia-like homeobox-containing genes. The encoded protein may play a role in the regulation of vertebrate limb myogenesis. Mutations in the related mouse protein may be associated with craniofacial and/or skeletal abnormalities, in addition to neurovascular dysfunction observed in Alzheimer's disease. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | MOX-2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 33kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human MEOX2. AA range:151-200 |
| Specificity | MOX-2 Polyclonal Antibody detects endogenous levels of MOX-2 protein. |
| Gene Name | MEOX2 |
| Protein Name | Homeobox protein MOX-2 |
| Other Name | MEOX2; / GAX; / MOX2; / Homeobox protein MOX-2; / Growth arrest-specific homeobox; / Mesenchyme homeobox 2 |
| Species | Human |
| Gene ID | 4223 |
| Uniprot | P50222, |
| Species.1 | Mouse |
| Gene ID.1 | 17286 |
| Uniprot.1 | P32443, |
| Species.2 | Rat |
| Gene ID.2 | 29279 |
| Uniprot.2 | P39020 |
| Cellular Localization | Nucleus . Nucleus speckle . |
| Tissue Expression | Embryo,Heart,Skin, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Role in mesoderm induction and its earliest regional specification, somitogenesis, and myogenic and sclerotomal differentiation. May have a regulatory role when quiescent vascular smooth muscle cells reenter the cell cycle.,polymorphism:The poly-His region of MEOX2 is polymorphic and the number of His varies in the population.,similarity:Contains 1 homeobox DNA-binding domain.,subunit:Interacts with RNF10.,tissue specificity:Embryo and placenta., |
