SKU: WP17550 Categories: ,

MPP2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP17550-100
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Product details

Background:

Palmitoylated membrane protein 2 is a member of a family of membrane-associated proteins termed MAGUKs (membrane-associated guanylate kinase homologs). MAGUKs interact with the cytoskeleton and regulate cell proliferation, signaling pathways, and intracellular junctions. Palmitoylated membrane protein 2 contains a conserved sequence, called the SH3 (src homology 3) motif, found in several other proteins that associate with the cytoskeleton and are suspected to play important roles in signal transduction. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetMPP2
ReactivityHuman, Mouse
ApplicationsWB, IHC
MW(Calculated)63kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human MPP2 AA range: 439-489
SpecificityThis antibody detects endogenous levels of MPP2 at Human/Mouse
Gene NameMPP2 DLG2
Protein NameMPP2
Other Name
SpeciesHuman
Gene ID4355
UniprotQ14168,
Species.1Mouse
Gene ID.150997
Uniprot.1Q9WV34
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm, cytoskeleton . Membrane . Cell projection, dendrite . Cell junction, synapse, postsynaptic density . Prominently expressed in the postsynaptic densities of dendritic spines, is also detected in dendritic shafts. .
Tissue Expression
Signaling_pathway
Research Areas
Functionsimilarity:Belongs to the MAGUK family.,similarity:Contains 1 guanylate kinase-like domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 2 L27 domains.,
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