$999.00
O-GlcNAc Specific Antibody Conjugated Agarose Beadsis an immunoaffinity enrichment tool for O-GlcNAc-modified peptides in mass spectrometry-based proteomics. The highly specific antibody selectively captures target modified peptides without cross-reactivity, is applicable to all species, efficiently enriches low-abundance peptides and reduces background interference, delivering stable and reliable results for O-GlcNAc modification research.
| Target | O-GlcNAc |
| Reactivity | Species Independent |
| Application | IAC, IAP, IP |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | |
| Conjugate | Agarose Beads |
| Modification | O-GlcNAcylation |
| Modified site | Ser(S) /Thr (T) |
| Recommended dilution ratio | |
| Composition | |
| Purification process | Protein A |
| Purity | |
| Storage | 50% slurry in PBS pH7.4, 0.05% Proclin 300. Ensure thorough mixing before each use. Wide-mouth pipette tips are recommended. In case of difficulty in aspiration due to improper operation, additional Storage Buffer can be added at your discretion. |
| Stability | 12 months from date of receipt / reconstitution, 2 to 8 °C as supplied |
| Clonal | Recombinant monoclonal |
| Clone Number | |
| Immunogen | |
| Sequence | |
| Specificity | |
| Gene name | |
| Protein Name | |
| Alternative name | |
| Organism-1 | |
| GeneID-1 | |
| SwissProt-1 | |
| Organism-2 | |
| GeneID-2 | |
| SwissProt-2 | |
| Organism-3 | |
| GeneID-3 | |
| SwissProt-3 | |
| Organism-4 | |
| GeneID-4 | |
| SwissProt-4 | |
| Background | O-GlcNAc (short for O-linked β-N-acetylglucosamine) is a reversible enzymatic post-translational modification found on serine and threonine residues of nucleocytoplasmic proteins. The modification is characterized by a β-glycosidic bond between the hydroxyl group of serine or threonine side chains and N-acetylglucosamine (GlcNAc).It is widely involved in the regulation of diverse cellular processes, including transcription, cell cycle, signal transduction, and stress response. Dysregulation of O-GlcNAcylation has been closely linked to cancer, neurodegeneration, diabetes, and inflammatory diseases. Notably, elevated O-GlcNAc levels in many cancers have been reported to suppress apoptosis by inhibiting caspase activation. |
| Cellular Localization |
