U-Blot® pan Cadherin Rabbit mAb
WR4398 Various whole cell lysates were separated by 4-20% SDS-PAGE, and the primary antibody was used at 4°C, over night with a 1:5000 dilution . The Dylight 800-conjugated Goat anti-Rabbit antibody(Cat:WS0446) was used to detect the antibody.
WR4398
Price range: $268.00 through $328.00
Product details
Background:Cadherin is a kind of adhesion protein which belongs to a transmembrane glycoprotein superfamily. It plays an important role in structural integrity of epithelia. This antibody can detect many isotypes of cadherin.
Specifications
| Size | 50μL/100μL |
| Target | cadherin pan |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC, IF, IP, ELISA |
| MW(Calculated) | 100kD |
| MW(Observed) | 130kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | IHC 1:1000-1:4000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; IP 1:50-1:200; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM0617R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | CDH1/CDH3/CDH4/CDH6 |
| Protein Name | cadherin |
| Other Name | Cadherin-1; / CAM 120/80; / Epithelial cadherin; / E-cadherin; / Uvomorulin; / CD324; / Cadherin-2; / CDw325; / Neural cadherin; / N-cadherin1 Publication; / CD325; / Cadherin-3; / Placental cadherin; / P-cadherin; / Cadherin-4; / Retinal cadherin; / R-CAD; / R-cadherin; / Cadherin-6; / Kidney cadherin; / K-cadherin; / CDH6 |
| Species | Human |
| Gene ID | |
| Uniprot | P55285;P22223;P12830;P55283 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membranous |
| Tissue Expression | Non-neural epithelial tissues. |
| Signaling_pathway | |
| Research Areas | >>Rap1 signaling pathway; / >>Apelin signaling pathway; / >>Hippo signaling pathway; / >>Cell adhesion molecules; / >>Adherens junction; / >>Bacterial invasion of epithelial cells; / >>Pathways in cancer; / >>Endometrial cancer; / >>Thyroid cancer; / >>Melanoma; / >>Bladder cancer; / >>Gastric cancer |
| Function |
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