Product details
Background:Enables 2-oxoglutarate-dependent dioxygenase activity. [provided by Alliance of Genome Resources, Feb 2025]
U-Blot® PHYHD1 Rabbit mAb
WR4648 Western Blot analysis of A549 whole cell lysates were separated by 4-20% SDS-PAGE, and the membrane was blotted with anti-PHYHD1 rabbit mAb. The HRP-conjugated Goat anti-Rabbit IgG(H + L) antibody was used to detect the antibody.
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | PHYHD1 |
| Reactivity | Human |
| Applications | WB, IF, ICC, FC |
| MW(Calculated) | |
| MW(Observed) | 32kD |
| Host Species | Rabbit |
| Isotype | IgG,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:1000-5000; ICC/IF 1:100-300; FC 1:100-300 |
| Formulation | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Purification | Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | RM0782R |
| Immunogen | The specific immunogen used to produce this antibody is proprietary information. |
| Specificity | Endogenous |
| Gene Name | PHYHD1 |
| Protein Name | Phytanoyl-CoA dioxygenase domain-containing protein 1; Protein PHYHD1 |
| Other Name | PHYHD1; / Phytanoyl-CoA dioxygenase domain-containing protein 1; / Protein PHYHD1 |
| Species | Human |
| Gene ID | 254295 |
| Uniprot | Q5SRE7, |
| Species.1 | Mouse |
| Gene ID.1 | 227696 |
| Uniprot.1 | Q9DB26, |
| Species.2 | Rat |
| Gene ID.2 | 296621 |
| Uniprot.2 | Q5BJP9 |
| Cellular Localization | |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | 2-oxoglutarate(2OG)-dependent dioxygenase that catalyzes the conversion of 2-oxoglutarate to succinate and CO(2) in an iron-dependent manner (PubMed:21530488). However, does not couple 2OG turnover to the hydroxylation of acyl-coenzyme A derivatives, implying that it is not directly involved in phytanoyl coenzyme-A metabolism (PubMed:21530488). Does not show detectable activity towards fatty acid CoA thioesters (PubMed:21530488). {ECO:0000269|PubMed:21530488}.; [Isoform 2]: Isoform 2 probably lacks enzyme activity. {ECO:0000269|PubMed:21530488}.; [Isoform 3]: Isoform 3 probably lacks enzyme activity. {ECO:0000269|PubMed:21530488}. |
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