RBMS1 Polyclonal Antibody
Ucallm_WP3356-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of a small family of proteins which bind single stranded DNA/RNA. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. Several transcript variants, resulting from alternative splicing and encoding different isoforms, have been described. A pseudogene for this locus is found on chromosome 12. [provided by RefSeq, Feb 2009],
Specifications
| Size | 50μL/100μL |
| Target | RBMS1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 44kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | RBMS1 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | RBMS1 C2orf12 MSSP MSSP1 SCR2 |
| Protein Name | RNA-binding motif, single-stranded-interacting protein 1 (Single-stranded DNA-binding protein MSSP-1) (Suppressor of CDC2 with RNA-binding motif 2) |
| Other Name | |
| Species | Human |
| Gene ID | 5937 |
| Uniprot | P29558, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q91W59, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q5PQP1 |
| Cellular Localization | Nucleus. |
| Tissue Expression | Highest amounts are found in placenta, lung and heart. |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Expressed at highest levels during the G1 to S transition of the cell cycle.,Function:Single-stranded DNA binding protein that interacts with the region upstream of the C-myc gene. Binds specifically to the DNA sequence motif 5'-[AT]CT[AT][AT]T-3'. Probably has a role in DNA replication.,sequence Caution:Translation N-terminally extended.,similarity:Contains 2 RRM (RNA recognition motif) domains.,tissue specificity:Highest amounts are found in placenta, lung and heart., |
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