RDH14 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | RDH14 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA, IHC |
| MW(Calculated) | 37kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human RDH14 AA range: 283-333 |
| Specificity | This antibody detects endogenous levels of RDH14 at Human/Mouse |
| Gene Name | RDH14 PAN2 UNQ529/PRO1072 |
| Protein Name | RDH14 |
| Other Name | |
| Species | Human |
| Gene ID | 57665 |
| Uniprot | Q9HBH5, |
| Species.1 | Mouse |
| Gene ID.1 | 105014 |
| Uniprot.1 | Q9ERI6 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | nucleus,mitochondrion,lysosomal membrane,endoplasmic reticulum,endoplasmic reticulum membrane,membrane, |
| Tissue Expression | Widely expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,cofactor:Magnesium.,enzyme regulation:Activated by ADP.,Function:Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides. Helps to regulate adenosine levels.,Function:Exhibits an oxidoreductive catalytic activity towards retinoids. Most efficient as an NADPH-dependent retinal reductase. Displays high activity toward 9-cis and all-trans-retinol. No steroid dehydrogenase activity detected.,similarity:Belongs to the 5'-nucleotidase type 3 family.,similarity:Belongs to the short-chain dehydrogenases/reductases (SDR) family.,tissue specificity:Expressed in brain, kidney, pancreas and placenta.,tissue specificity:Highly expressed in testis, placenta and pancreas. Detected at lower levels in heart, kidney, liver and lung., |
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