$365.00
Background:The protein encoded byThis gene is a member of a family of membrane glycoproteins. This glycoprotein provides selectins with carbohydrate ligands. It may also play a role in tumor cell metastasis. [provided by RefSeq, Jul 2008]
| Size | 100μL |
| Target | LAMP1 |
| Reactivity | Human |
| Applications | ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | ELISA 1:5000-100000 |
| Formulation | Phosphate-buffered solution |
| Purification | Recombinant Expression and Affinity purified |
| Storage | -15°C to -25°C/1 year(Avoid freeze / thaw cycles) |
| Concentration | Please check the information on the tube |
| Clonality | |
| Clone Number | VF0528 |
| Immunogen | Purified recombinant Human LAMP1 |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of LAMP1 protein. |
| Gene Name | LAMP1 |
| Protein Name | Lysosome-associated membrane glycoprotein 1 (LAMP-1) (Lysosome-associated membrane protein 1) (CD107 antigen-like family member A) (CD antigen CD107a) |
| Other Name | LAMP1; / Lysosome-associated membrane glycoprotein 1; / LAMP-1; / Lysosome-associated membrane protein 1; / CD107 antigen-like family member A; / CD107a |
| Species | Human |
| Gene ID | 3916 |
| Uniprot | P11279 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein . Endosome membrane; Single-pass type I membrane protein . Lysosome membrane; Single-pass type I membrane protein . Late endosome membrane; Single-pass type I membrane protein . Cytolytic granule membrane; Single-pass type I membrane protein . This protein shuttles between lysosomes, endosomes, and the plasma membrane (By similarity). Colocalizes with OSBPL1A at the late endosome (PubMed:16176980). . |
| Tissue Expression | Leukocyte,Liver,Placenta,Skin |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Phagosome;Cellular Processes >> Transport and catabolism >> Lysosome;Cellular Processes >> Transport and catabolism >> Autophagy - animal |
| Research Areas | |
| Function | Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.,PTM:O- and N-glycosylated; some of the 18 N-linked glycans are polylactosaminoglycans.,similarity:Belongs to the LAMP family.,subcellular location:This protein shuttles between lysosomes, endosomes, and the plasma membrane., |
