Recombinant CD235a Fc-Fused Nanobody (VF0071)
Ucallm_WN0203
$365.00
Product details
Background:Glycophorins A (GYPA) and B (GYPB) are major sialoglycoproteins of the human erythrocyte membrane which bear the antigenic determinants for the MN and Ss blood groups. In addition to the M or N and S or s antigens that commonly occur in all populations, about 40 related variant phenotypes have been identified. These variants include all the variants of the Miltenberger complex and several isoforms of Sta, as well as Dantu, Sat, He, Mg, and deletion variants Ena, S-s-U- and Mk. Most of the variants are the result of gene recombinations between GYPA and GYPB. [provided by RefSeq, Jul 2008]
Specifications
| Size | 100μL |
| Target | Glycophorin A |
| Reactivity | Human |
| Applications | ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | ELISA 1:5000-100000 |
| Formulation | Phosphate-buffered solution |
| Purification | Recombinant Expression and Affinity purified |
| Storage | -15°C to -25°C/1 year(Avoid freeze / thaw cycles) |
| Concentration | Please check the information on the tube |
| Clonality | |
| Clone Number | VF0071 |
| Immunogen | Purified recombinant Human CD235a |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD235a protein. |
| Gene Name | GYPA GPA |
| Protein Name | Glycophorin-A (MN sialoglycoprotein) (PAS-2) (Sialoglycoprotein alpha) (CD antigen CD235a) |
| Other Name | GYPA; / GPA; / Glycophorin-A; / MN sialoglycoprotein; / PAS-2; / Sialoglycoprotein alpha; / CD235a; / CD235a nanobody |
| Species | Human |
| Gene ID | 2993 |
| Uniprot | P02724 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein . Appears to be colocalized with SLC4A1. |
| Tissue Expression | Blood,Bone marrow,Kidney,Liver,Lung,Miltenberger class V |
| Signaling_pathway | Organismal Systems >> Immune system >> Hematopoietic cell lineage |
| Research Areas | |
| Function | Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors and also binds influenza virus.,online information:Blood group antigen gene mutation database,polymorphism:Along with GYPB, GYPA is responsible for the MNS blood group system.,similarity:Belongs to the glycophorin A family., |
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