Recombinant CD48 Fc-Fused Nanobody (VF0198)
Ucallm_WN0388
$365.00
Product details
Background:This gene encodes a member of the CD2 subfamily of immunoglobulin-like receptors which includes SLAM (signaling lymphocyte activation molecules) proteins. The encoded protein is found on the surface of lymphocytes and other immune cells, dendritic cells and endothelial cells, and participates in activation and differentiation pathways in these cells. The encoded protein does not have a transmembrane domain, however, but is held at the cell surface by a GPI anchor via a C-terminal domain which maybe cleaved to yield a soluble form of the receptor. Multiple transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq, Dec 2011]
Specifications
| Size | 100μL |
| Target | CD48 |
| Reactivity | Human |
| Applications | ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | ELISA 1:5000-100000; Flow Cyt 1-2μg/Test |
| Formulation | Phosphate-buffered solution |
| Purification | Recombinant Expression and Affinity purified |
| Storage | -15°C to -25°C/1 year(Avoid freeze / thaw cycles) |
| Concentration | Please check the information on the tube |
| Clonality | |
| Clone Number | VF0381 |
| Immunogen | Purified recombinant Human CD48 |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD48 protein. |
| Gene Name | CD48 BCM1 BLAST1 |
| Protein Name | CD48 antigen (B-lymphocyte activation marker BLAST-1) (BCM1 surface antigen) (Leukocyte antigen MEM-102) (SLAM family member 2) (SLAMF2) (Signaling lymphocytic activation molecule 2) (TCT.1) (CD antigen CD48) |
| Other Name | CD48; / BCM1; / BLAST1; / CD48 antigen; / B-lymphocyte activation marker BLAST-1; / BCM1 surface antigen; / Leukocyte antigen MEM-102; / TCT.1; / CD48; / CD48 nanobody |
| Species | Human |
| Gene ID | 962 |
| Uniprot | P09326 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor . Secreted . |
| Tissue Expression | Expressed in mature B-cells, but not in T-cells or monocytes. |
| Signaling_pathway | Organismal Systems >> Immune system >> Natural killer cell mediated cytotoxicity |
| Research Areas | |
| Function | Ligand for CD2. Might facilitate interaction between activated lymphocytes. Probably involved in regulating T-cell activation.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain., |
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