Recombinant CD56 Fc-Fused Nanobody (VF0635)
Ucallm_WN0418
$365.00
Product details
Background:This gene encodes a cell adhesion protein which is a member of the immunoglobulin superfamily. The encoded protein is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. The encoded protein has been shown to be involved in development of the nervous system, and for cells involved in the expansion of T cells and dendritic cells which play an important role in immune surveillance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2011]
Specifications
| Size | 100μL |
| Target | CD56 |
| Reactivity | Human |
| Applications | ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | ELISA 1:5000-100000 |
| Formulation | Phosphate-buffered solution |
| Purification | Recombinant Expression and Affinity purified |
| Storage | -15°C to -25°C/1 year(Avoid freeze / thaw cycles) |
| Concentration | Please check the information on the tube |
| Clonality | |
| Clone Number | VF0144 |
| Immunogen | Purified recombinant Human CD56 |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD56 protein. |
| Gene Name | NCAM1 NCAM |
| Protein Name | Neural cell adhesion molecule 1 (N-CAM-1) (NCAM-1) (CD antigen CD56) |
| Other Name | antigen MSK39 identified by monoclonal 5.1H11; / antigen recognized by monoclonal 5.1H11; / CD56; / cell adhesion molecule; / neural; / 1; / MSK 39; / MSK39; / N-CAM-1; / NCAM 1; / NCAM; / NCAM C; / NCAM-1; / NCAM1; / NCAM1_HUMAN; / NCAMC; / Neural cell adhesion molecule 1; / Neural cell adhesion molecule NCAM; / OTTHUMP00000235666; / CD56 nanobody |
| Species | Human |
| Gene ID | 4684 |
| Uniprot | P13591 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | [Isoform 1]: Cell membrane; Single-pass type I membrane protein.; [Isoform 2]: Cell membrane; Single-pass type I membrane protein.; [Isoform 3]: Cell membrane; Lipid-anchor, GPI-anchor.; [Isoform 4]: Cell membrane; Lipid-anchor, GPI-anchor .; [Isoform 5]: Secreted.; [Isoform 6]: Secreted . |
| Tissue Expression | Expressed in some types of immune cells. Expressed at low levels on the surface of freshly isolated T-cells and natural killer (NK) cells, predominantly on CD8+ T-cells (mainly memory/effector, but not naive cells) and on both CD16+ and CD16- NK cells. T-cell expression levels are variable among individuals. Not detected in B-cells, naive or helper T-cells, monocytes, nor neutrophils (at protein level). Not detected in dendritic cells. |
| Signaling_pathway | Human Diseases >> Neurodegenerative disease >> Prion disease;Environmental Information Processing >> Signaling molecules and interaction >> Cell adhesion molecules |
| Research Areas | |
| Function | This protein is a cell adhesion molecule involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc.,online information:N-CAM 140,online information:NCAM entry,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 5 Ig-like C2-type (immunoglobulin-like) domains., |
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