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Background:This gene encodes a member of the calcium dependent lectin superfamily of type II transmembrane receptors. Expression of the encoded protein is induced upon activation of T lymphocytes, and may play a role in proliferation. Furthermore, the protein may act to transmit signals in natural killer cells and platelets. [provided by RefSeq, Aug 2011]
| Size | 100μL |
| Target | CD69 |
| Reactivity | Human |
| Applications | ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | ELISA 1:5000-100000; Flow Cyt 1-2μg/Test |
| Formulation | Phosphate-buffered solution |
| Purification | Recombinant Expression and Affinity purified |
| Storage | -15°C to -25°C/1 year(Avoid freeze / thaw cycles) |
| Concentration | Please check the information on the tube |
| Clonality | |
| Clone Number | VF0592 |
| Immunogen | Purified recombinant Human CD69 |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD69 protein. |
| Gene Name | CD69 CLEC2C |
| Protein Name | Early activation antigen CD69 (Activation inducer molecule) (AIM) (BL-AC/P26) (C-type lectin domain family 2 member C) (EA1) (Early T-cell activation antigen p60) (GP32/28) (Leukocyte surface antigen Leu-23) (MLR-3) (CD antigen CD69) |
| Other Name | CD69; / CLEC2C; / Early activation antigen CD69; / Activation inducer molecule; / AIM; / BL-AC/P26; / C-type lectin domain family 2 member C; / EA1; / Early T-cell activation antigen p60; / GP32/28; / Leukocyte surface antigen Leu-23; / MLR-3; / CD antigen CD69; / CD69 nanobody |
| Species | Human |
| Gene ID | 969 |
| Uniprot | Q07108 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass type II membrane protein. |
| Tissue Expression | B-cell,Blood |
| Signaling_pathway | |
| Research Areas | |
| Function | developmental stage:Earliest inducible cell surface glycoprotein acquired during lymphoid activation.,Involved in lymphocyte proliferation and functions as a signal transmitting receptor in lymphocytes, natural killer (NK) cells, and platelets.,induction:By antigens, mitogens or activators of PKC on the surface of T and B-lymphocytes. By interaction of IL-2 with the p75 IL-2R on the surface of NK cells.,online information:CD69,PTM:Constitutive Ser/Thr phosphorylation in both mature thymocytes and activated T-lymphocytes.,similarity:Contains 1 C-type lectin domain.,subunit:Homodimer; disulfide-linked.,tissue specificity:Expressed on the surface of activated T-cells, B-cells, natural killer cells, neutrophils, eosinophils, epidermal Langerhans cells and platelets., |
