Recombinant CD83 Fc-Fused Nanobody (VF0083)
Ucallm_WN0547
$365.00
Product details
Background:The protein encoded byThis gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form ofThis protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found forThis gene. [provided by RefSeq, Oct 2011]
Specifications
| Size | 100μL |
| Target | CD83 |
| Reactivity | Human |
| Applications | ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | ELISA 1:5000-100000; Flow Cyt 1-2μg/Test |
| Formulation | Phosphate-buffered solution |
| Purification | Recombinant Expression and Affinity purified |
| Storage | -15°C to -25°C/1 year(Avoid freeze / thaw cycles) |
| Concentration | Please check the information on the tube |
| Clonality | |
| Clone Number | VF0001 |
| Immunogen | Purified recombinant Human CD83 |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD83 protein. |
| Gene Name | CD83 |
| Protein Name | CD83 antigen (hCD83) (B-cell activation protein) (Cell surface protein HB15) (CD antigen CD83) |
| Other Name | CD83; / CD83 antigen; / hCD83; / B-cell activation protein; / Cell surface protein HB15; / CD antigen CD83; / CD83 nanobody |
| Species | Human |
| Gene ID | 9308 |
| Uniprot | Q01151 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Expression | CD8 on thymus-derived T-cells usually consists of a disulfide-linked alpha/CD8A and a beta/CD8B chain. Less frequently, CD8 can be expressed as a CD8A homodimer. A subset of natural killer cells, memory T-cells, intraepithelial lymphocytes, monocytes and dendritic cells expresses CD8A homodimers. Expressed at the cell surface of plasmacytoid dendritic cells upon herpes simplex virus-1 stimulation. |
| Signaling_pathway | |
| Research Areas | |
| Function | May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.,online information:CD83 antigen,similarity:Contains 1 Ig-like V-type (immunoglobulin-like) domain.,subunit:Monomer.,tissue specificity:Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells., |
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