Recombinant CD94 Fc-Fused Nanobody (VF0244)
Ucallm_WN0574
$365.00
Product details
Background:Natural killer (NK) cells are a distinct lineage of lymphocytes that mediate cytotoxic activity and secrete cytokines upon immune stimulation. Several genes of the C-type lectin superfamily, including members of the NKG2 family, are expressed by NK cells and may be involved in the regulation of NK cell function. KLRD1 (CD94) is an antigen preferentially expressed on NK cells and is classified as a type II membrane protein because it has an external C terminus. Three transcript variants encoding two different isoforms have been found forThis gene. [provided by RefSeq, Jul 2008]
Specifications
| Size | 100μL |
| Target | CD94 |
| Reactivity | Human |
| Applications | ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | ELISA 1:5000-100000 |
| Formulation | Phosphate-buffered solution |
| Purification | Recombinant Expression and Affinity purified |
| Storage | -15°C to -25°C/1 year(Avoid freeze / thaw cycles) |
| Concentration | Please check the information on the tube |
| Clonality | |
| Clone Number | VF0573 |
| Immunogen | Purified recombinant Human CD94 |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of CD94 protein. |
| Gene Name | KLRD1 CD94 |
| Protein Name | Natural killer cells antigen CD94 (KP43) (Killer cell lectin-like receptor subfamily D member 1) (NK cell receptor) (CD antigen CD94) |
| Other Name | KLRD1; / CD94; / Natural killer cells antigen CD94; / KP43; / Killer cell lectin-like receptor subfamily D member 1; / NK cell receptor; / CD antigen CD94; / CD94 nanobody |
| Species | Human |
| Gene ID | 3824 |
| Uniprot | Q13241 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Single-pass type II membrane protein . |
| Tissue Expression | |
| Signaling_pathway | Organismal Systems >> Immune system >> Natural killer cell mediated cytotoxicity;Organismal Systems >> Immune system >> Antigen processing and presentation;Human Diseases >> Immune disease >> Graft-versus-host disease |
| Research Areas | |
| Function | Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.,online information:CD94,similarity:Contains 1 C-type lectin domain.,subunit:Can form disulfide-bonded heterodimer with NKG2 family members.,tissue specificity:Natural killer cells., |
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