Recombinant IFN-α1 Fc-Fused Nanobody (VF0457)
Ucallm_WN0610
$365.00
Product details
Background:The protein encoded by this gene is produced by macrophages and has antiviral activity. This gene is intronless and the encoded protein is secreted. [provided by RefSeq, Sep 2011],
Specifications
| Size | 100μL |
| Target | IFNa |
| Reactivity | Human |
| Applications | ELISA |
| MW(Calculated) | |
| MW(Observed) | |
| Host Species | |
| Isotype | IgG2a,Kappa |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | ELISA 1:5000-100000 |
| Formulation | Phosphate-buffered solution |
| Purification | Recombinant Expression and Affinity purified |
| Storage | -15°C to -25°C/1 year(Avoid freeze / thaw cycles) |
| Concentration | Please check the information on the tube |
| Clonality | |
| Clone Number | VF0541 |
| Immunogen | Purified recombinant Human IFNa |
| Specificity | This recombinant monoclonal antibody can detects endogenous levels of IFNa protein. |
| Gene Name | IFNA1/IFNA13 |
| Protein Name | Interferon alpha-1/13 |
| Other Name | IFNA1; / IFNA13; / Interferon alpha-1/13; / IFN-alpha-1/13; / Interferon alpha-D; / LeIF D; / IFNa nanobody |
| Species | Human |
| Gene ID | 3439 |
| Uniprot | P01562 |
| Species.1 | |
| Gene ID.1 | |
| Uniprot.1 | |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted. |
| Tissue Expression | Leukocyte,Liver,Placenta,Skin |
| Signaling_pathway | Cellular Processes >> Cell growth and death >> Necroptosis;Organismal Systems >> Immune system >> Toll-like receptor signaling pathway;Organismal Systems >> Immune system >> NOD-like receptor signaling pathway;Organismal Systems >> Immune system >> RIG-I-like receptor signaling pathway;Organismal Systems >> Immune system >> Cytosolic DNA-sensing pathway;Organismal Systems >> Immune system >> Natural killer cell mediated cytotoxicity;Human Diseases >> Cancer: overview >> Pathways in cancer;Human Diseases >> Immune disease >> Autoimmune thyroid disease;Environmental Information Processing >> Signal transduction >> JAK-STAT signaling pathway;Environmental Information Processing >> Signal transduction >> PI3K-Akt signaling pathway;Environmental Information Processing >> Signaling molecules and interaction >> Cytokine-cytokine receptor interaction |
| Research Areas | |
| Function | Function:Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.,miscellaneous:Interferons alpha-1 and alpha-13 have identical protein sequences.,polymorphism:Two forms exist; alpha-1a (shown here) and alpha-1b.,similarity:Belongs to the alpha/beta interferon family., |
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