SKU: WP14244 Categories: ,

Relaxin 3 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14244-100
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Product details

Background:

relaxin 3(RLN3) Homo sapiens This gene encodes a member of the relaxin family of insulin-like hormones that is expressed predominantly in the brain and plays a role in physiological processes such as stress, memory and appetite regulation. The encoded protein is a precursor that is proteolytically processed to generate a heterodimeric mature form consisting A and B chains interlinked by disulfide bonds. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2015],

Specifications

Size50μL/100μL
TargetRelaxin 3
ReactivityHuman, Mouse, Rat
ApplicationsIHC, IF, ELISA
MW(Calculated)15kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:100-1:300; ELISA 1:40000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from the Internal region of human Relaxin 3.
SpecificityRelaxin 3 Polyclonal Antibody detects endogenous levels of Relaxin 3 protein.
Gene NameRLN3
Protein NameRelaxin-3
Other NameRLN3; / INSL7; / RXN3; / ZINS4; / Relaxin-3; / Insulin-like peptide INSL7; / Insulin-like peptide 7; / Prorelaxin H3
SpeciesHuman
Gene ID117579
UniprotQ8WXF3,
Species.1Mouse
Gene ID.1
Uniprot.1Q8CHK2
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationSecreted.
Tissue Expression
Signaling_pathwayOrganismal Systems >> Endocrine system >> Relaxin signaling pathway
Research Areas>>Neuroactive ligand-receptor interaction; / >>Relaxin signaling pathway
FunctionFunction:May play a role in neuropeptide signaling processes. Ligand for LGR7, relaxin-3 receptor-1 (GPCR135) and relaxin-3 receptor-2 (GPCR142).,similarity:Belongs to the insulin family.,subunit:Heterodimer of a B chain and an A chain linked by two disulfide bonds.,
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