Name: RFA1 rabbit pAb
SKU: WP17805
Price: 268 USD
Availability: InStock

RFA1 rabbit pAb

Ucallm_WP17805-50

Price range: $268.00 through $328.00

Size

100μl

50μl

Clear

SKU: WP17805-100

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Product details

Background:

function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., similarity:Belongs to the replication factor A protein 1 family., subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,

Specifications

Size	50μL/100μL
Target	RPA70
Reactivity	Human, Mouse, Rat, Monkey
Applications	WB, ELISA, IHC
MW(Calculated)	68kD
MW(Observed)
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	Synthesized peptide derived from human RFA1
Specificity	This antibody detects endogenous levels of Human,Monkey,Mouse,Rat RFA1
Gene Name	RPA1 REPA1 RPA70
Protein Name	Replication protein A 70 kDa DNA-binding subunit
Other Name	Replication protein A 70 kDa DNA-binding subunit; / RP-A p70; / Replication factor A protein 1; / RF-A protein 1; / Single-stranded DNA-binding protein
Species	Human
Gene ID	6117
Uniprot	P27694,
Species.1	Mouse
Gene ID.1	68275
Uniprot.1	Q8VEE4
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Nucleus . Nucleus, PML body . Enriched in PML bodies in cells displaying alternative lengthening of their telomeres. .
Tissue Expression
Signaling_pathway
Research Areas	>>DNA replication; / >>Nucleotide excision repair; / >>Mismatch repair; / >>Homologous recombination; / >>Fanconi anemia pathway
Function	Function:It participates in a very early step in initiation. RP-A is a single-stranded DNA-binding protein. Absolutely required for simian virus 40 DNA replication in vitro.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the replication factor A protein 1 family.,subunit:Heterotrimer of 70, 32 and 14 kDa chains. The DNA-binding activity may reside exclusively on the 70 kDa subunit. Interacts with RIP and XPA. Interacts with RPA4.,

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RFA1 rabbit pAb

Product details

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RFA1 rabbit pAb

Product details

Specifications

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