Price range: $268.00 through $328.00
Background:
Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP44 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008],
| Size | 50μL/100μL |
| Target | USP44 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 81kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; ELISA 1:40000; Not yet tested in other applications. |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human USP44. AA range:211-260 |
| Specificity | USP44 Polyclonal Antibody detects endogenous levels of USP44 protein. |
| Gene Name | USP44 |
| Protein Name | Ubiquitin carboxyl-terminal hydrolase 44 |
| Other Name | USP44; / Ubiquitin carboxyl-terminal hydrolase 44; / Deubiquitinating enzyme 44; / Ubiquitin thioesterase 44; / Ubiquitin-specific-processing protease 44 |
| Species | Human |
| Gene ID | 84101 |
| Uniprot | Q9H0E7, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8C2S0 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . Peaks in interphase, with relatively low levels maintained throughout mitosis. . |
| Tissue Expression | Expressed in testis. Expressed at high levels in T-cell acute lymphoblastic leukemia. |
| Signaling_pathway | |
| Research Areas | |
| Function | Catalytic activity:Ubiquitin C-terminal thioester + H(2)O = ubiquitin + a thiol.,similarity:Belongs to the peptidase C19 family.,similarity:Contains 1 UBP-type zinc finger.,tissue specificity:Expressed in testis., |
