SKU: WP14266 Categories: ,

RFX2 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14266-100
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Product details

Background:

This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetRFX2
ReactivityHuman, Mouse, Rat
ApplicationsIHC, IF, ELISA
MW(Calculated)80kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioIHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human RFX2. AA range:661-710
SpecificityRFX2 Polyclonal Antibody detects endogenous levels of RFX2 protein.
Gene NameRFX2
Protein NameDNA-binding protein RFX2
Other NameRFX2; / DNA-binding protein RFX2; / Regulatory factor X 2
SpeciesHuman
Gene ID5990
UniprotP48378,
Species.1Mouse
Gene ID.1
Uniprot.1P48379
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus . Cytoplasm . Mainly expressed in the nucleus and at lower level in cytoplasm. .
Tissue Expression
Signaling_pathway
Research Areas
Functionsimilarity:Belongs to the RFX family.,
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