Price range: $268.00 through $328.00
Background:
This gene encodes a member of the repulsive guidance molecule family. The encoded protein is a glycosylphosphatidylinositol-anchored glycoprotein that functions as an axon guidance protein in the developing and adult central nervous system. This protein may also function as a tumor suppressor in some cancers. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],
| Size | 50μL/100μL |
| Target | RGMA |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 49kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | RGMA Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | RGMA RGM |
| Protein Name | Repulsive guidance molecule A (RGM domain family member A) |
| Other Name | |
| Species | Human |
| Gene ID | 56963 |
| Uniprot | Q96B86, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q6PCX7 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor . |
| Tissue Expression | Retina,Teratocarcinoma,Testis,Uterus, |
| Signaling_pathway | Environmental Information Processing >> Signal transduction >> TGF-beta signaling pathway |
| Research Areas | >>TGF-beta signaling pathway; / >>Axon guidance |
| Function | Function:Repulsive guidance molecules (Rgm) are involved in the guidance of growth cones of the developing neurons.,similarity:Belongs to the repulsive guidance molecule (RGM) family., |
