SKU: WP8987 Categories: ,

RGS3 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8987-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetRGS3
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)132kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human RGS3
SpecificityThis antibody detects endogenous levels of RGS3 at Human, Mouse,Rat
Gene NameRGS3
Protein NameRegulator of G-protein signaling 3 (RGP3) (RGS3)
Other Name
SpeciesHuman
Gene ID5998
UniprotP49796,
Species.1Mouse
Gene ID.150780
Uniprot.1Q9DC04,
Species.2Rat
Gene ID.254293
Uniprot.2P49797
Cellular LocalizationCytoplasm . Nucleus . Cell membrane; Peripheral membrane protein . Long isoforms are cytoplasmic and associated with the plasma membrane (PubMed:9858594). Short isoforms are nuclear (PubMed:10749886).
Tissue Expression
Signaling_pathway
Research Areas
FunctionDown-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.
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