Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human RGS3
Specificity
This antibody detects endogenous levels of RGS3 at Human, Mouse,Rat
Gene Name
RGS3
Protein Name
Regulator of G-protein signaling 3 (RGP3) (RGS3)
Other Name
Species
Human
Gene ID
5998
Uniprot
P49796,
Species.1
Mouse
Gene ID.1
50780
Uniprot.1
Q9DC04,
Species.2
Rat
Gene ID.2
54293
Uniprot.2
P49797
Cellular Localization
Cytoplasm . Nucleus . Cell membrane; Peripheral membrane protein . Long isoforms are cytoplasmic and associated with the plasma membrane (PubMed:9858594). Short isoforms are nuclear (PubMed:10749886).
Tissue Expression
Signaling_pathway
Research Areas
Function
Down-regulates signaling from heterotrimeric G-proteins by increasing the GTPase activity of the alpha subunits, thereby driving them into their inactive GDP-bound form. Down-regulates G-protein-mediated release of inositol phosphates and activation of MAP kinases.