Ribosomal Protein S4X Polyclonal Antibody
Ucallm_WP14335-50
Price range: $268.00 through $328.00
Product details
Background:
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, Y-linked (RPS4Y). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. This gene is not subject to X-inactivation. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseud
Specifications
| Size | 50μL/100μL |
| Target | Ribosomal Protein S4X |
| Reactivity | Human, Mouse, Rat, Cat |
| Applications | WB, IF, ELISA, IHC |
| MW(Calculated) | |
| MW(Observed) | 30kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300; IF 1:200-1:1000; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human RPS4X. AA range:81-130 |
| Specificity | Ribosomal Protein S4X Polyclonal Antibody detects endogenous levels of Ribosomal Protein S4X protein. |
| Gene Name | RPS4X |
| Protein Name | 40S ribosomal protein S4 X isoform |
| Other Name | RPS4X; / CCG2; / RPS4; / SCAR; / 40S ribosomal protein S4; / X isoform; / SCR10; / Single copy abundant mRNA protein |
| Species | Human |
| Gene ID | 6191 |
| Uniprot | P62701, |
| Species.1 | Mouse |
| Gene ID.1 | 20102 |
| Uniprot.1 | P62702, |
| Species.2 | Rat |
| Gene ID.2 | 100362640 |
| Uniprot.2 | P62703 |
| Cellular Localization | Cytoplasm . Localized in cytoplasmic mRNP granules containing untranslated mRNAs. |
| Tissue Expression | Adipose tissue,Brain,Cerebellum,Eye,Muscle,Placenta,Thymus, |
| Signaling_pathway | |
| Research Areas | >>Ribosome; / >>Coronavirus disease - COVID-19 |
| Function | miscellaneous:This isoform is encoded on the X chromosome.,similarity:Belongs to the ribosomal protein S4e family.,similarity:Contains 1 S4 RNA-binding domain., |
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