SKU: WP14339 Categories: ,

Ribosomal Protein S8 Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP14339-100
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Product details

Background:

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S8E family of ribosomal proteins. It is located in the cytoplasm. Increased expression of this gene in colorectal tumors and colon polyps compared to matched normal colonic mucosa has been observed. This gene is co-transcribed with the small nucleolar RNA genes U38A, U38B, U39, and U40, which are located in its fourth, fifth, first, and second introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetRibosomal Protein S8
ReactivityHuman, Mouse, Rat
ApplicationsWB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)30kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenThe antiserum was produced against synthesized peptide derived from human RPS8. AA range:111-160
SpecificityRibosomal Protein S8 Polyclonal Antibody detects endogenous levels of Ribosomal Protein S8 protein.
Gene NameRPS8
Protein Name40S ribosomal protein S8
Other NameRPS8; / OK/SW-cl.83; / 40S ribosomal protein S8
SpeciesHuman
Gene ID6202
UniprotP62241,
Species.1Mouse
Gene ID.120116
Uniprot.1P62242,
Species.2Rat
Gene ID.2297756
Uniprot.2P62243
Cellular LocalizationCytoplasm . Membrane; Lipid-anchor . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Tissue ExpressionColon adenocarcinoma,Liver,Placenta,Thalamus,Uterus,
Signaling_pathway
Research Areas>>Ribosome; / >>Coronavirus disease - COVID-19
Functionsimilarity:Belongs to the ribosomal protein S8e family.,
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