Product details
Background:
RIMB1 rabbit pAb
Ucallm_WP17468-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | RIMB1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, IHC |
| MW(Calculated) | 204kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; IHC 1:50-300 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human RIMB1 AA range: 24-74 |
| Specificity | This antibody detects endogenous levels of RIMB1 at Human/Mouse/Rat |
| Gene Name | BZRAP1 KIAA0612 RBP1 RIMBP1 |
| Protein Name | RIMB1 |
| Other Name | |
| Species | Human |
| Gene ID | 9256 |
| Uniprot | O95153, |
| Species.1 | Mouse |
| Gene ID.1 | 207777 |
| Uniprot.1 | Q7TNF8, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q9JIR0 |
| Cellular Localization | Cytoplasm . Mitochondrion . Preferentially expressed in the mitochondria in the presence of TSPO. |
| Tissue Expression | Predominantly expressed in brain, pituitary gland and thymus in adults. In adult brain, highest expression found in temporal lobe and the putamen, followed by amygdala, caudate nucleus, cerebral cortex, occipital and frontal lobe. A high expression level is also observed in fetal tissues like brain, heart, kidney and thymus. |
| Signaling_pathway | |
| Research Areas | |
| Function | Caution:PubMed:9915832 demonstrated interaction with BZRP but later PubMed:12435798 demonstrated in the rat ortholog that is not associated with BZRP in the brain.,Domain:The SH3 and proline-rich domain is required for the interaction with BZRP and the second SH3 domain mediates binding to a proline-rich motif in RIMS1 and RIMS2.,similarity:Belongs to the RIMBP family.,similarity:Contains 3 fibronectin type-III domains.,similarity:Contains 3 SH3 domains.,subcellular location:Preferentially expressed in the mitochondria in the presence of BZRP.,subunit:Interacts with RIMS1 and RIMS2 (By similarity). Interacts with BZRP.,tissue specificity:Predominantly expressed in brain, pituitary gland and thymus in adults. In adult brain, highest expression found in temporal lobe and the putamen, followed by amygdala, caudate nucleus, cerebral cortex, occipital and frontal lobe. A high expression level is also observed in fetal tissues like brain, heart, kidney and thymus., |
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