Product details
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RNASEH2B rabbit pAb
Ucallm_WP7289-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | RNASEH2B |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 34kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human RNASEH2B |
| Specificity | This antibody detects endogenous levels of RNASEH2B at Human, Mouse,Rat |
| Gene Name | RNASEH2B DLEU8 |
| Protein Name | Ribonuclease H2 subunit B (RNase H2 subunit B) (Aicardi-Goutieres syndrome 2 protein) (AGS2) (Deleted in lymphocytic leukemia 8) (Ribonuclease HI subunit B) |
| Other Name | |
| Species | Human |
| Gene ID | 79621 |
| Uniprot | Q5TBB1, |
| Species.1 | Mouse |
| Gene ID.1 | 67153 |
| Uniprot.1 | Q80ZV0, |
| Species.2 | Rat |
| Gene ID.2 | 361056 |
| Uniprot.2 | Q5XI96 |
| Cellular Localization | Nucleus . |
| Tissue Expression | Widely expressed. |
| Signaling_pathway | |
| Research Areas | |
| Function | Non catalytic subunit of RNase H2, an endonuclease that specifically degrades the RNA of RNA:DNA hybrids. Participates in DNA replication, possibly by mediating the removal of lagging-strand Okazaki fragment RNA primers during DNA replication. Mediates the excision of single ribonucleotides from DNA:RNA duplexes. |
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