ROBO4 Polyclonal Antibody
Ucallm_WP2582-50
Price range: $268.00 through $328.00
Product details
Background:
function:Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins., similarity:Belongs to the immunoglobulin superfamily. ROBO family., similarity:Contains 2 fibronectin type-III domains., similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains., subunit:Interacts with SLIT2 and ENAH., tissue specificity:Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types.,
Specifications
| Size | 50μL/100μL |
| Target | ROBO4 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 110kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | ROBO4 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | ROBO4 UNQ421/PRO3674 |
| Protein Name | Roundabout homolog 4 (Magic roundabout) |
| Other Name | |
| Species | Human |
| Gene ID | 54538 |
| Uniprot | Q8WZ75, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | Q8C310, |
| Species.2 | Rat |
| Gene ID.2 | |
| Uniprot.2 | Q80W87 |
| Cellular Localization | integral component of membrane,extracellular exosome, |
| Tissue Expression | Specifically expressed in endothelial cells. Expressed in endothelial and intimal cells of the ascending aorta (PubMed:30455415). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Receptor for Slit proteins, at least for SLIT2, and seems to be involved in angiogenesis and vascular patterning. May mediate the inhibition of primary endothelial cell migration by Slit proteins.,similarity:Belongs to the immunoglobulin superfamily. ROBO family.,similarity:Contains 2 fibronectin type-III domains.,similarity:Contains 2 Ig-like C2-type (immunoglobulin-like) domains.,subunit:Interacts with SLIT2 and ENAH.,tissue specificity:Specifically expressed in endothelial cells. Expressed at sites of angiogenesis in different tumor types., |
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