This gene encodes a protein that contains a tetratricopeptide repeat domain. The encoded protein also interacts with the rotavirus non-structural protein NSP3. [provided by RefSeq, Jul 2008],
Specifications
Size
50μL/100μL
Target
RoXaN
Reactivity
Human
Applications
WB, IHC, IF, ELISA
MW(Calculated)
MW(Observed)
111kD
Host Species
Rabbit
Isotype
IgG
Conjugate/Modification
Unmodified
Recommended Dilution Ratio
WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
The antiserum was produced against synthesized peptide derived from human ZC3H7B. AA range:851-900
Specificity
RoXaN Polyclonal Antibody detects endogenous levels of RoXaN protein.
Nucleus . Nuclear localization seems to be depleted upon rotavirus A infection.
Tissue Expression
Brain,Lung,Trachea,Uterus,
Signaling_pathway
Research Areas
Function
similarity:Contains 1 C2H2-type zinc finger.,similarity:Contains 3 TPR repeats.,similarity:Contains 4 C3H1-type zinc fingers.,subcellular location:Nuclear localization seems to be depleted upon rotavirus A infection.,subunit:Interacts (via LD motif) with rotavirus A NSP3 (via the coiled-coil region).,