RPN2 rabbit pAb
Ucallm_WP6943-50
Price range: $268.00 through $328.00
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | RPN2 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 69kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human RPN2 |
| Specificity | This antibody detects endogenous levels of RPN2 at Human, Mouse,Rat |
| Gene Name | RPN2 |
| Protein Name | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2 (Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 63 kDa subunit) (RIBIIR) (Ribophorin II) (RPN-II) (Ribophorin-2) |
| Other Name | |
| Species | Human |
| Gene ID | 6185 |
| Uniprot | P04844, |
| Species.1 | Mouse |
| Gene ID.1 | 20014 |
| Uniprot.1 | Q9DBG6, |
| Species.2 | Rat |
| Gene ID.2 | 64701 |
| Uniprot.2 | P25235 |
| Cellular Localization | Endoplasmic reticulum . Endoplasmic reticulum membrane; Multi-pass membrane protein . |
| Tissue Expression | Expressed in all tissues tested. |
| Signaling_pathway | Genetic Information Processing >> Folding, sorting and degradation >> Protein processing in endoplasmic reticulum |
| Research Areas | |
| Function | Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol-pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation . N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the endoplasmic reticulum (ER). All subunits are required for a maximal enzyme activity. |
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