Price range: $268.00 through $328.00
Background:
The protein encoded by this gene is a small GTPase involved in diverse processes including angiogenesis, vascular homeostasis and regeneration, cell adhesion, and neuronal axon guidance. Mutations in this gene are found in many invasive cancers. [provided by RefSeq, Jul 2015],
| Size | 50μL/100μL |
| Target | RRAS |
| Reactivity | Human, Mouse, Rat |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 23kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human protein . at AA range: 1-80 |
| Specificity | RRAS Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | RRAS |
| Protein Name | Ras-related protein R-Ras (p23) |
| Other Name | Ras-related protein R-Ras; / p23 |
| Species | Human |
| Gene ID | 6237 |
| Uniprot | P10301, |
| Species.1 | Mouse |
| Gene ID.1 | 20130 |
| Uniprot.1 | P10833, |
| Species.2 | Rat |
| Gene ID.2 | 361568 |
| Uniprot.2 | D3Z8L7 |
| Cellular Localization | Cell membrane; Lipid-anchor; Cytoplasmic side . Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS). |
| Tissue Expression | Adipocyte,Brain,Uterus, |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Autophagy - animal;Cellular Processes >> Transport and catabolism >> Mitophagy - animal;Cellular Processes >> Cell growth and death >> Cellular senescence;Cellular Processes >> Cell motility >> Regulation of actin cytoskeleton;Environmental Information Processing >> Signal transduction >> MAPK signaling pathway;Environmental Information Processing >> Signal transduction >> Ras signaling pathway;Environmental Information Processing >> Signal transduction >> Rap1 signaling pathway;Environmental Information Processing >> Signal transduction >> Apelin signaling pathway;Environmental Information Processing >> Signal transduction >> Phospholipase D signaling pathway;Environmental Information Processing >> Signal transduction >> cAMP signaling pathway |
| Research Areas | >>MAPK signaling pathway; / >>Ras signaling pathway; / >>Rap1 signaling pathway; / >>cAMP signaling pathway; / >>Phospholipase D signaling pathway; / >>Mitophagy - animal; / >>Autophagy - animal; / >>Cellular senescence; / >>Axon guidance; / >>Apelin signaling pathway; / >>C-type lectin receptor signaling pathway; / >>Regulation of actin cytoskeleton; / >>Salmonella infection; / >>Proteoglycans in cancer |
| Function | Function:Regulates the organization of the actin cytoskeleton.,similarity:Belongs to the small GTPase superfamily. Ras family.,subcellular location:Inner surface of plasma membrane possibly with attachment requiring acylation of the C-terminal cysteine (By similarity with RAS).,subunit:Interacts with PLCE1., |
