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RS1 rabbit pAb
Ucallm_WP8482-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | RS1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 25kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human RS1 |
| Specificity | This antibody detects endogenous levels of RS1 at Human, Mouse |
| Gene Name | RS1 XLRS1 |
| Protein Name | Retinoschisin (X-linked juvenile retinoschisis protein) |
| Other Name | |
| Species | Human |
| Gene ID | 6247 |
| Uniprot | O15537, |
| Species.1 | Mouse |
| Gene ID.1 | 20147 |
| Uniprot.1 | Q9Z1L4 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Secreted . Cell membrane; Peripheral membrane protein; Extracellular side . Binds to phosphatidylserine-containing lipid membranes and embeds itself partially into the lipid bilayer. Lipid-binding requires the presence of Ca(2+) ions. . |
| Tissue Expression | Restricted to the retina (at protein level) (PubMed:10915776). Detected in the inner segment of the photoreceptors, the inner nuclear layer, the inner plexiform layer and the ganglion cell layer (at protein level). At the macula, expressed in both the outer and inner nuclear layers and in the inner plexiform layer (at protein level) (PubMed:10915776). Detected in retina (PubMed:9326935). Detected only within the photoreceptor cell layer, most prominently within the inner segments of the photoreceptors (PubMed:10915776). Undetectable in the inner plexiform layers and the inner nuclear layer (PubMed:10915776). |
| Signaling_pathway | |
| Research Areas | |
| Function | Binds negatively charged membrane lipids, such as phosphatidylserine and phosphoinositides (By similarity). May play a role in cell-cell adhesion processes in the retina, via homomeric interaction between octamers present on the surface of two neighboring cells . Required for normal structure and function of the retina . |
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