SKU: WP0793 Categories: ,

RS3A Polyclonal Antibody

Price range: $268.00 through $328.00

SKU: WP0793-100
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Product details

Background:

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 40S subunit. The protein belongs to the S3AE family of ribosomal proteins. It is located in the cytoplasm. Disruption of the gene encoding rat ribosomal protein S3a, also named v-fos transformation effector protein, in v-fos-transformed rat cells results in reversion of the transformed phenotype. This gene is co-transcribed with the U73A and U73B small nucleolar RNA genes, which are located in its fourth and third introns, respectively. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Alternatively spliced transcript variants have

Specifications

Size50μL/100μL
TargetRS3A
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA
MW(Calculated)
MW(Observed)29kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; ELISA 1:5000-20000
FormulationLiquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human protein . at AA range: 190-270
SpecificityRS3A Polyclonal Antibody detects endogenous levels of protein.
Gene NameRPS3A FTE1 MFTL
Protein Name40S ribosomal protein S3a (v-fos transformation effector protein) (Fte-1)
Other Name
SpeciesHuman
Gene ID6189
UniprotP61247,
Species.1Mouse
Gene ID.1
Uniprot.1P97351,
Species.2Rat
Gene ID.2
Uniprot.2P49242
Cellular LocalizationCytoplasm . Nucleus . Localized in cytoplasmic mRNP granules containing untranslated mRNAs.
Tissue ExpressionB-cell,Epithelium,Eye,Liver,Muscle,Ovary,Placenta,Skin,Testis,Uterus,
Signaling_pathway
Research Areas>>Ribosome; / >>Coronavirus disease - COVID-19
Functionsimilarity:Belongs to the ribosomal protein S3Ae family.,subunit:Binds with high affinity to IPO4.,
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