S23A1 rabbit pAb
Ucallm_WP16189-50
Price range: $268.00 through $328.00
Product details
Background:
The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],
Specifications
| Size | 50μL/100μL |
| Target | S23A1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 66kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human S23A1 AA range: 237-287 |
| Specificity | This antibody detects endogenous levels of S23A1 at Human/Mouse/Rat |
| Gene Name | SLC23A1 SVCT1 YSPL3 |
| Protein Name | S23A1 |
| Other Name | |
| Species | Human |
| Gene ID | 9963 |
| Uniprot | Q9UHI7, |
| Species.1 | Mouse |
| Gene ID.1 | 20522 |
| Uniprot.1 | Q9Z2J0, |
| Species.2 | Rat |
| Gene ID.2 | 50621 |
| Uniprot.2 | Q9WTW7 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . |
| Tissue Expression | Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus. |
| Signaling_pathway | |
| Research Areas | >>Vitamin digestion and absorption |
| Function | Alternative products:Experimental confirmation may be lacking for some isoforms,Function:Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.,miscellaneous:Treatment with the protein kinase C stimulator PMA results in a 10-fold decrease in ascorbate accumulation in transfected cells.,PTM:Phosphorylated.,similarity:Belongs to the xanthine/uracil permease family. SLC23A subfamily.,tissue specificity:Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus., |
Please login to post questions
Related products
