Product details
Background:
This gene is located within the Smith-Magenis syndrome region on chromosome 17. It encodes a protein of unknown function. [provided by RefSeq, Jul 2008],
S47A1 rabbit pAb
Ucallm_WP3593-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | S47A1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 65kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human S47A1 AA range: 158-208 |
| Specificity | This antibody detects endogenous levels of S47A1 at Human/Mouse/Rat |
| Gene Name | SLC47A1 MATE1 |
| Protein Name | S47A1 |
| Other Name | Multidrug and toxin extrusion protein 1; / MATE-1; / hMATE-1; / Solute carrier family 47 member 1 |
| Species | Human |
| Gene ID | 55244 |
| Uniprot | Q96FL8, |
| Species.1 | Mouse |
| Gene ID.1 | 67473 |
| Uniprot.1 | Q8K0H1, |
| Species.2 | Rat |
| Gene ID.2 | 360539 |
| Uniprot.2 | Q5I0E9 |
| Cellular Localization | Cell membrane; Multi-pass membrane protein . Predominantly localized at the plasma membrane but also found in intracellular organelles. |
| Tissue Expression | Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes). |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes.,similarity:Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.,subcellular location:Predominantly localized at the plasma membrane but also found in intracellular organelles.,tissue specificity:Expressed in adrenal gland, and to a lower extent in liver, skeletal muscle and kidney (especially found in luminal membranes of the urinary tubules, bile caniculi and brush border membranes)., |
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