S7A14 rabbit pAb
Ucallm_WP3748-50
Price range: $268.00 through $328.00
Product details
Background:
This gene is predicted to encode a glycosylated, cationic amino acid transporter protein with 14 transmembrane domains. This gene is primarily expressed in skin fibroblasts, neural tissue, and primary endothelial cells and its protein is predicted to mediate lysosomal uptake of cationic amino acids. Mutations in this gene are associated with autosomal recessive retinitis pigmentosa. In mice, this gene is expressed in the photoreceptor layer of the retina where its expression increases over the course of retinal development and persists in the mature retina. [provided by RefSeq, Apr 2014],
Specifications
| Size | 50μL/100μL |
| Target | S7A14 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 85kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human S7A14 AA range: 50-100 |
| Specificity | This antibody detects endogenous levels of S7A14 at Human/Mouse |
| Gene Name | SLC7A14 KIAA1613 |
| Protein Name | S7A14 |
| Other Name | Probable cationic amino acid transporter; / Solute carrier family 7 member 14 |
| Species | Human |
| Gene ID | 57709 |
| Uniprot | Q8TBB6, |
| Species.1 | Mouse |
| Gene ID.1 | 241919 |
| Uniprot.1 | Q8BXR1 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Lysosome membrane; Multi-pass membrane protein . Exhibits a punctated pattern in the cytoplasm, which partially ovelaps with lysosomes. |
| Tissue Expression | Expressed in skin fibroblasts. |
| Signaling_pathway | |
| Research Areas | |
| Function | sequence Caution:Translated as Glu.,similarity:Belongs to the amino acid-polyamine-organocation (APC) superfamily. Cationic amino acid transporter (CAT) (TC 2.A.3.3) family., |
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