Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Source
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Purity
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SLC38A4
Sequence
Specificity
This antibody detects endogenous levels of SLC38A4 at Human, Mouse,Rat
Gene Name
SLC38A4 ATA3 NAT3 SNAT4
Protein Name
Sodium-coupled neutral amino acid transporter 4 (Amino acid transporter A3) (Na(+)-coupled neutral amino acid transporter 4) (Solute carrier family 38 member 4) (System A amino acid transporter 3) (System N amino acid transporter 3)
Other Name
Species
Human
Gene ID-1
55089
Uniprot
Q969I6,
Species.1
Mouse
Gene ID-2
69354
Uniprot.1
Q8R1S9,
Species.2
Rat
Gene ID-3
170573
Uniprot.2
Q9EQ25
Organism-4
Gene ID-4
SwissProt-4
Background
Cellular Localization
Cell membrane; Multi-pass membrane protein .
Tissue Expression
Detected in embryonic and adult liver, and at lower levels in adult muscle, kidney and pancreas. Detected in placenta syncytiotrophoblasts throughout gestation. Detected in fetal blood vessels.
Signaling_pathway
Research Areas
Function
Sodium-dependent amino acid transporter. Mediates electrogenic symport of neutral amino acids and sodium ions. Has a broad specificity, with a preference for Ala, followed by His, Cys, Asn, Ser, Gly, Val, Thr, Gln and Met. May mediate sodium-independent transport of cationic amino acids, such as Arg and Lys. Amino acid uptake is pH-dependent, with low transport activities at pH 6.5, intermediate at pH 7.0 and highest between pH 7.5 and 8.5.