Price range: $268.00 through $328.00
Background:
function:Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis., similarity:Contains 1 MYND-type zinc finger., similarity:Contains 1 SET domain., subunit:Interacts with HDAC1, HDAC2 and HDAC3.,
| Size | 50μL/100μL |
| Target | SMYD1 |
| Reactivity | Rat |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 56kD |
| Host Species | Mouse |
| Isotype | |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:100 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | |
| Clonality | Monoclonal |
| Clone Number | 18A8 |
| Immunogen | Purified recombinant human SMYD1 protein fragments expressed in E.coli. |
| Specificity | This antibody detects endogenous levels of SMYD1 and does not cross-react with related proteins. |
| Gene Name | smyd1 |
| Protein Name | |
| Other Name | BOP; / CD8 beta opposite; / CD8b opposite; / Histone lysine N methyltransferase SMYD1; / KMT3D; / SET and MYND domain-containing protein 1; / SMYD1; / SMYD1_HUMAN; / Zinc finger MYND domain containing 18; / ZMYND18; / ZMYND22; / zinc finger, MYND domain containing 18. |
| Species | Human |
| Gene ID | 150572 |
| Uniprot | Q8NB12, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P97443 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Cytoplasm . Nucleus . |
| Tissue Expression | Expression seems mostly restricted to heart and skeletal muscle. |
| Signaling_pathway | |
| Research Areas | >>Lysine degradation; / >>Metabolic pathways |
| Function | Function:Acts as a transcriptional repressor. Essential for cardiomyocyte differentiation and cardiac morphogenesis.,similarity:Contains 1 MYND-type zinc finger.,similarity:Contains 1 SET domain.,subunit:Interacts with HDAC1, HDAC2 and HDAC3., |
