Name: SNAI 1 Polyclonal Antibody
SKU: WP14526
Price: 268 USD
Availability: InStock

SNAI 1 Polyclonal Antibody

Ucallm_WP14526-50

Price range: $268.00 through $328.00

Size

100μl

50μl

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SKU: WP14526-100

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Product details

Background:

snail family transcriptional repressor 1(SNAI1) Homo sapiens The Drosophila embryonic protein snail is a zinc finger transcriptional repressor which downregulates the expression of ectodermal genes within the mesoderm. The nuclear protein encoded by this gene is structurally similar to the Drosophila snail protein, and is also thought to be critical for mesoderm formation in the developing embryo. At least two variants of a similar processed pseudogene have been found on chromosome 2. [provided by RefSeq, Jul 2008],

Specifications

Size	50μL/100μL
Target	SNAI1
Reactivity	Human, Mouse, Monkey
Applications	WB, IP, IHC, IF, ELISA
MW(Calculated)
MW(Observed)	29kD
Host Species	Rabbit
Isotype	IgG
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	WB 1:500-1:2000; IHC 1:100-1:300; IF 1:200-1:1000; ELISA 1:5000; Not yet tested in other applications. / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration	1 mg/ml
Clonality	Polyclonal
Clone Number
Immunogen	The antiserum was produced against synthesized peptide derived from human SNAI1. AA range:215-264
Specificity	SNAI 1 Polyclonal Antibody detects endogenous levels of SNAI 1 protein.
Gene Name	SNAI1
Protein Name	Zinc finger protein SNAI1(snail)
Other Name	SNAI1; / SNAH; / Zinc finger protein SNAI1; / Protein snail homolog 1; / Protein sna
Species	Human
Gene ID	6615
Uniprot	O95863,
Species.1	Mouse
Gene ID.1	20613
Uniprot.1	Q02085
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Nucleus . Cytoplasm . Once phosphorylated (probably on Ser-107, Ser-111, Ser-115 and Ser-119) it is exported from the nucleus to the cytoplasm where subsequent phosphorylation of the destruction motif and ubiquitination involving BTRC occurs. .
Tissue Expression	Expressed in a variety of tissues with the highest expression in kidney. Expressed in mesenchymal and epithelial cell lines.
Signaling_pathway	Cellular Processes >> Cellular community - eukaryotes >> Adherens junction
Research Areas	>>Adherens junction
Function	Function:Seems to be involved in embryonic mesoderm formation. Binds to 3 E-boxes of the E-cadherin gene promoter and represses its transcription.,similarity:Belongs to the snail C2H2-type zinc-finger protein family.,similarity:Contains 4 C2H2-type zinc fingers.,tissue specificity:Expressed in a variety of tissues with the highest expression in kidney.,

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SNAI 1 Polyclonal Antibody

Product details

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SNAI 1 Polyclonal Antibody

Product details

Specifications

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