SKU: WP7503 Categories: ,

SOAT2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP7503-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetSOAT2
ReactivityHuman, Mouse, Rat
ApplicationsWB
MW(Calculated)57kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human SOAT2
SpecificityThis antibody detects endogenous levels of SOAT2 at Human, Mouse,Rat
Gene NameSOAT2 ACACT2 ACAT2
Protein NameSterol O-acyltransferase 2 (Acyl-coenzyme A:cholesterol acyltransferase 2) (ACAT-2) (Cholesterol acyltransferase 2)
Other Name
SpeciesHuman
Gene ID8435
UniprotO75908,
Species.1Mouse
Gene ID.1223920
Uniprot.1O88908,
Species.2Rat
Gene ID.2266770
Uniprot.2Q7TQM4
Cellular LocalizationEndoplasmic reticulum membrane; Multi-pass membrane protein .
Tissue ExpressionExpression seems confined in hepatocytes and enterocytes.
Signaling_pathway
Research Areas
FunctionCatalyzes the formation of fatty acid-cholesterol esters, which are less soluble in membranes than cholesterol . Plays a role in lipoprotein assembly and dietary cholesterol absorption . Utilizes oleoyl-CoA ((9Z)-octadecenoyl-CoA) and linolenoyl-CoA ((9Z,12Z,15Z)-octadecatrienoyl-CoA) as substrates . May provide cholesteryl esters for lipoprotein secretion from hepatocytes and intestinal mucosa .; [Isoform 2]: Has lower enzymatic activity compared to isoform 1.; [Isoform 3]: Has lower enzymatic activity compared to isoform 1.
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