Price range: $268.00 through $328.00
Background:
SRY-box 3(SOX3) Homo sapiens This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. Mutations in this gene have been associated with X-linked mental retardation with growth hormone deficiency. [provided by RefSeq, Jul 2008],
| Size | 50μL/100μL |
| Target | SOX3 |
| Reactivity | Human, Mouse |
| Applications | WB, ELISA |
| MW(Calculated) | |
| MW(Observed) | 49kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000; ELISA 1:5000-20000 |
| Formulation | Liquid in PBS containing 50% glycerol,0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from part region of human protein |
| Specificity | SOX3 Polyclonal Antibody detects endogenous levels of protein. |
| Gene Name | SOX3 |
| Protein Name | Transcription factor SOX-3 |
| Other Name | |
| Species | Human |
| Gene ID | 6658 |
| Uniprot | P41225, |
| Species.1 | Mouse |
| Gene ID.1 | |
| Uniprot.1 | P53784 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus. |
| Tissue Expression | Brain,Spinal cord, |
| Signaling_pathway | |
| Research Areas | |
| Function | Caution:Was originally (PubMed:1614875) termed SOX-9.,Disease:Defects in SOX3 are a cause of panhypopituitarism X-linked (PHPX) [MIM:312000]. Affected individuals have absent infundibulum, anterior pituitary hypoplasia, and ectopic posterior pituitary.,Disease:Defects in SOX3 are the cause of mental retardation X-linked with isolated growth hormone deficiency (MRXGH) [MIM:300123].,similarity:Contains 1 HMG box DNA-binding domain., |
