SKU: WP3710 Categories: ,

SOX5 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP3710-100
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Product details

Background:

This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],

Specifications

Size50μL/100μL
TargetSOX5
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)
MW(Observed)85kD
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human SOX5 AA range: 43-93
SpecificityThis antibody detects endogenous levels of SOX5 at Human/Mouse
Gene NameSOX5
Protein NameSOX5
Other NameTranscription factor SOX-5
SpeciesHuman
Gene ID6660
UniprotP35711,
Species.1Mouse
Gene ID.120678
Uniprot.1P35710
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationNucleus .
Tissue ExpressionBrain,Fetal heart,Heart,Liver,Testis,
Signaling_pathway
Research Areas
FunctionFunction:Binds specifically to the DNA sequence 5'-AACAAT-3'. Activates transcription of COL2A1 and AGC1 in vitro.,similarity:Contains 1 HMG box DNA-binding domain.,
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