SOX5 rabbit pAb
Product details
Background:
This gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins. The encoded protein may play a role in chondrogenesis. A pseudogene of this gene is located on chromosome 8. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | SOX5 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | |
| MW(Observed) | 85kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SOX5 AA range: 43-93 |
| Specificity | This antibody detects endogenous levels of SOX5 at Human/Mouse |
| Gene Name | SOX5 |
| Protein Name | SOX5 |
| Other Name | Transcription factor SOX-5 |
| Species | Human |
| Gene ID | 6660 |
| Uniprot | P35711, |
| Species.1 | Mouse |
| Gene ID.1 | 20678 |
| Uniprot.1 | P35710 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus . |
| Tissue Expression | Brain,Fetal heart,Heart,Liver,Testis, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Binds specifically to the DNA sequence 5'-AACAAT-3'. Activates transcription of COL2A1 and AGC1 in vitro.,similarity:Contains 1 HMG box DNA-binding domain., |
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