Sp2 Polyclonal Antibody
Ucallm_WP14549-50
Price range: $268.00 through $328.00
Product details
Background:
This gene encodes a member of the Sp subfamily of Sp/XKLF transcription factors. Sp family proteins are sequence-specific DNA-binding proteins characterized by an amino-terminal trans-activation domain and three carboxy-terminal zinc finger motifs. This protein contains the least conserved DNA-binding domain within the Sp subfamily of proteins, and its DNA sequence specificity differs from the other Sp proteins. It localizes primarily within subnuclear foci associated with the nuclear matrix, and can activate or in some cases repress expression from different promoters. [provided by RefSeq, Jul 2008],
Specifications
| Size | 50μL/100μL |
| Target | Sp2 |
| Reactivity | Human, Mouse |
| Applications | WB, IHC, IF, ELISA |
| MW(Calculated) | |
| MW(Observed) | 64kD |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:20000; IF 1:50-200 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004) |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | The antiserum was produced against synthesized peptide derived from human SP2. AA range:471-520 |
| Specificity | Sp2 Polyclonal Antibody detects endogenous levels of Sp2 protein. |
| Gene Name | SP2 |
| Protein Name | Transcription factor Sp2 |
| Other Name | SP2; / KIAA0048; / Transcription factor Sp2 |
| Species | Human |
| Gene ID | 6668 |
| Uniprot | Q02086, |
| Species.1 | Mouse |
| Gene ID.1 | 78912 |
| Uniprot.1 | Q9D2H6 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Nucleus. |
| Tissue Expression | Bone marrow,Brain,Lung,Lymph,Spleen, |
| Signaling_pathway | |
| Research Areas | |
| Function | Function:Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites.,similarity:Belongs to the Sp1 C2H2-type zinc-finger protein family.,similarity:Contains 3 C2H2-type zinc fingers., |
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