SKU: WP8035 Categories: ,

SPACA3 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP8035-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetSPACA3
ReactivityHuman, Mouse
ApplicationsWB
MW(Calculated)24kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human SPACA3
SpecificityThis antibody detects endogenous levels of SPACA3 at Human, Mouse
Gene NameSPACA3 LYC3 LYZL3 SLLP1 SPRASA UNQ424/PRO862
Protein NameSperm acrosome membrane-associated protein 3 (Cancer/testis antigen 54) (CT54) (Lysozyme-like acrosomal sperm-specific secretory protein ALLP-17) (Lysozyme-like protein 3) (Sperm lysozyme-like protein 1) (Sperm protein reactive with antisperm antibodies) (Sperm protein reactive with ASA) [Cleaved into: Sperm acrosome membrane-associated protein 3, membrane form; Sperm acrosome membrane-associated protein 3, processed form]
Other Name
SpeciesHuman
Gene ID124912
UniprotQ8IXA5,
Species.1Mouse
Gene ID.175622
Uniprot.1Q9D9X8
Species.2
Gene ID.2
Uniprot.2
Cellular Localization[Isoform 1]: Cytoplasmic vesicle, secretory vesicle, acrosome membrane; Single-pass type II membrane protein . Anterior acrosome in non-capacitated spermatozoa and retained in the equatorial segment and in the luminal face of both the inner and outer acrosomal membranes following capacitation and the acrosome reaction. .; [Isoform 2]: Secreted .
Tissue ExpressionThe processed form is expressed in sperm (at protein level). Expressed in testis, epididymis and placenta.
Signaling_pathway
Research Areas
FunctionSperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.
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