SPAM1 rabbit pAb
Product details
Background:
Specifications
| Size | 50μL/100μL |
| Target | SPAM1 |
| Reactivity | Human, Mouse, Rat |
| Applications | WB |
| MW(Calculated) | 56kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SPAM1 |
| Specificity | This antibody detects endogenous levels of SPAM1 at Human, Mouse,Rat |
| Gene Name | SPAM1 HYAL3 PH20 |
| Protein Name | Hyaluronidase PH-20 (Hyal-PH20) (Hyaluronoglucosaminidase PH-20) (Sperm adhesion molecule 1) (Sperm surface protein PH-20) |
| Other Name | SPAM1; / HYAL3; / PH20; / Hyaluronidase PH-20; / Hyal-PH20; / Hyaluronoglucosaminidase PH-20; / Sperm adhesion molecule 1; / Sperm surface protein PH-20 |
| Species | Human |
| Gene ID | 6677 |
| Uniprot | P38567, |
| Species.1 | Mouse |
| Gene ID.1 | 20690 |
| Uniprot.1 | P48794, |
| Species.2 | Rat |
| Gene ID.2 | 117037 |
| Uniprot.2 | Q62803 |
| Cellular Localization | Cell membrane; Lipid-anchor, GPI-anchor. |
| Tissue Expression | Testis. |
| Signaling_pathway | Cellular Processes >> Transport and catabolism >> Lysosome |
| Research Areas | |
| Function | Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg before reaching the zona pellucida. The cumulus cells are embedded in a matrix containing hyaluronic acid which is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid. |
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