WB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
1 mg/ml
Clonality
Polyclonal
Clone Number
Immunogen
Synthesized peptide derived from human SPAT2 AA range: 119-169
Specificity
This antibody detects endogenous levels of SPAT2 at Human
Gene Name
SPATA2 KIAA0757 PD1
Protein Name
SPAT2
Other Name
Species
Human
Gene ID
9825
Uniprot
Q9UM82
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular Localization
Cytoplasm . Nucleus . Detected in the tubular compartment of the testis and, in the cytoplasm of the Sertoli cells. .
Tissue Expression
Present at high level in Sertoli cells, but not detected in spermatogenic cells (at protein level) (PubMed:10222154, PubMed:11079456). Low expression in spleen, thymus and prostate (PubMed:10222154).
Signaling_pathway
Cellular Processes >> Cell growth and death >> Necroptosis
Research Areas
>>Necroptosis
Function
Function:May have a role in the regulation of spermatogenesis.,similarity:Belongs to the SPATA2 family.,tissue specificity:Highly expressed in Sertoli cells, but not detected in spermatogenic cells. Low expression in spleen, thymus and prostate.,