SKU: WP16668 Categories: ,

SPAT2 rabbit pAb

Price range: $268.00 through $328.00

SKU: WP16668-100
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Product details

Background:

Specifications

Size50μL/100μL
TargetSPAT2
ReactivityHuman, Mouse, Rat
ApplicationsWB, ELISA, IHC
MW(Calculated)57kD
MW(Observed)
Host SpeciesRabbit
IsotypeIgG
Conjugate/ModificationUnmodified
Recommended Dilution RatioWB 1:500-2000; IHC 1:50-300; ELISA 1:2000-20000 / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
FormulationLiquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
PurificationThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration1 mg/ml
ClonalityPolyclonal
Clone Number
ImmunogenSynthesized peptide derived from human SPAT2 AA range: 119-169
SpecificityThis antibody detects endogenous levels of SPAT2 at Human
Gene NameSPATA2 KIAA0757 PD1
Protein NameSPAT2
Other Name
SpeciesHuman
Gene ID9825
UniprotQ9UM82
Species.1
Gene ID.1
Uniprot.1
Species.2
Gene ID.2
Uniprot.2
Cellular LocalizationCytoplasm . Nucleus . Detected in the tubular compartment of the testis and, in the cytoplasm of the Sertoli cells. .
Tissue ExpressionPresent at high level in Sertoli cells, but not detected in spermatogenic cells (at protein level) (PubMed:10222154, PubMed:11079456). Low expression in spleen, thymus and prostate (PubMed:10222154).
Signaling_pathwayCellular Processes >> Cell growth and death >> Necroptosis
Research Areas>>Necroptosis
FunctionFunction:May have a role in the regulation of spermatogenesis.,similarity:Belongs to the SPATA2 family.,tissue specificity:Highly expressed in Sertoli cells, but not detected in spermatogenic cells. Low expression in spleen, thymus and prostate.,
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