Product details
Background:
- Please choose product options by visiting U-Blot® AP-2γ Rabbit mAb.
- Please choose product options by visiting Spectrin β II Polyclonal Antibody.
- Please choose product options by visiting SPINK9 rabbit pAb.
SPCS1 rabbit pAb
Ucallm_WP6665-50
Price range: $268.00 through $328.00
Specifications
| Size | 50μL/100μL |
| Target | SPCS1 |
| Reactivity | Human, Mouse |
| Applications | WB |
| MW(Calculated) | 19kD |
| MW(Observed) | |
| Host Species | Rabbit |
| Isotype | IgG |
| Conjugate/Modification | Unmodified |
| Recommended Dilution Ratio | WB 1:500-2000 |
| Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Storage | -15°C to -25°C/1 year(Do not lower than -25°C) |
| Concentration | 1 mg/ml |
| Clonality | Polyclonal |
| Clone Number | |
| Immunogen | Synthesized peptide derived from human SPCS1 |
| Specificity | This antibody detects endogenous levels of SPCS1 at Human, Mouse |
| Gene Name | SPCS1 SPC12 HSPC033 |
| Protein Name | Signal peptidase complex subunit 1 (Microsomal signal peptidase 12 kDa subunit) (SPase 12 kDa subunit) |
| Other Name | |
| Species | Human |
| Gene ID | 28972 |
| Uniprot | Q9Y6A9, |
| Species.1 | Mouse |
| Gene ID.1 | 69019 |
| Uniprot.1 | Q9D958 |
| Species.2 | |
| Gene ID.2 | |
| Uniprot.2 | |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein . |
| Tissue Expression | |
| Signaling_pathway | |
| Research Areas | |
| Function | Component of the signal peptidase complex (SPC) which catalyzes the cleavage of N-terminal signal sequences from nascent proteins as they are translocated into the lumen of the endoplasmic reticulum . Dispensable for SPC enzymatic activity (By similarity).; (Microbial infection) Required for the post-translational processing of proteins involved in virion assembly and secretion from flaviviruses such as West Nile virus (WNV), Japanese encephalitis virus (JEV), Dengue virus type 2 (DENV-2), Yellow Fever virus (YFV), Zika virus (ZIKV) and hepatitis C virus (HCV) . Plays a key role in the post-translational processing of flaviviral structural proteins prM, E, and NS1 . In HCV, it is involved in virion assembly where it promotes the interaction between HCV virus proteins NS2 and E2 . |
Please login to post questions
Related products
