Name: U-Blot® AP-2γ Rabbit mAb
SKU: WR5121
Price: 268 USD
Availability: InStock

U-Blot® AP-2γ Rabbit mAb

Ucallm_WR5121-50

Price range: $268.00 through $328.00

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50μl

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SKU: WR5121-50

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Product details

Background:transcription factor AP-2 gamma(TFAP2C) Homo sapiens The protein encoded by this gene is a sequence-specific DNA-binding transcription factor involved in the activation of several developmental genes. The encoded protein can act as either a homodimer or heterodimer with other family members and is induced during retinoic acid-mediated differentiation. It plays a role in the development of the eyes, face, body wall, limbs, and neural tube. [provided by RefSeq, Jul 2008],

Specifications

Size	50μL/100μL
Target	AP-2γ
Reactivity	Human, Mouse, Rat
Applications	WB, IHC, IF, ELISA
MW(Calculated)	49kD
MW(Observed)	49kD
Host Species	Rabbit
Isotype	IgG,Kappa
Conjugate/Modification	Unmodified
Recommended Dilution Ratio	IHC 1:200-1:1000; WB 1:2000-1:10000; IF 1:200-1:1000; ELISA 1:5000-1:20000; / Note: For IHC, we suggest antigen retrieval with TE buffer pH 9.0 (Cat#WT1004)
Formulation	PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA
Purification	Recombinant Antibody expressed in animal component-free (ACF) media, purified via Protein A affinity chromatography.
Storage	-15°C to -25°C/1 year(Do not lower than -25°C)
Concentration
Clonality	Monoclonal
Clone Number	RM1333R
Immunogen	The specific immunogen used to produce this antibody is proprietary information.
Specificity	Endogenous
Gene Name	TFAP2C
Protein Name	Transcription factor AP-2 gamma
Other Name	TFAP2C; / Transcription factor AP-2 gamma; / AP2-gamma; / Activating enhancer-binding protein 2 gamma; / Transcription factor ERF-1
Species	Human
Gene ID	7022
Uniprot	Q92754,
Species.1	Mouse
Gene ID.1	21420
Uniprot.1	Q61312
Species.2
Gene ID.2
Uniprot.2
Cellular Localization	Nucleus .
Tissue Expression	Liver,Mammary tumor,Ovary,Skin,
Signaling_pathway
Research Areas
Function	Domain:The WW-binding motif mediates interaction with WWOX.,Function:Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC.,induction:During retinoic acid-mediated differentiation.,online information:Activatin protein 2 entry,PTM:Sumoylated on Lys-10; which inhibits transcriptional activity.,similarity:Belongs to the AP-2 family.,subunit:Binds DNA as a dimer. Can form homodimers or heterodimers with other AP-2 family members (By similarity). Interacts with WWOX. Interacts with CITED4. Interacts with UBE2I.,

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U-Blot® AP-2γ Rabbit mAb

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U-Blot® AP-2γ Rabbit mAb

Product details

Specifications

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